High impact information on Mud Therapy

• Nine patients with biopsy-proved hepatocellular carcinoma underwent percutaneous ethanol ablation therapy (PEAT) with computed tomographic (CT) guidance [1].
• Sulphur bath and mud pack treatment for rheumatoid arthritis at the Dead Sea area [2].
• Serum levels of a prostaglandin and a leukotriene after thermal mud pack therapy [3].
• After the randomization, mud-bath applications reduced inflammation and at the end of the treatment the paw volume and the TNFa and IL-1beta serum levels were significantly tapered in comparison to the controls (p < 0.01) [4].
• Similarly, IL-1beta and TNF-alpha levels were unchanged through a 12 daily mud-pack treatment [5].

Associations of Mud Therapy with chemical compounds

• Our results show that mud packs together with antidepressant treatment are able to influence the HPA axis, stimulating increased levels of adrenocorticotropic hormone, cortisol and beta-endorphin serum levels [6].

Gene context of Mud Therapy

• One of the most interesting findings in this study was that MMP-3 serum levels were significantly lower in the treated groups, since this enzyme plays an important role in cartilage degradation, suggesting that mud bath therapy contributes to matrix integrity in OA cartilage [7].
• We investigated the influence of mud pack treatment, which is able to diminish TNF-alpha serum values, on specific TNF receptor (sTNF-R) levels [8].
• Mud pack treatment increases serum antioxidant defenses in osteoarthrosic patients [9].
• Because there is evidence that suggests that mud packs influence the main cytokines involved in cartilage damage, we tried to determine whether NO and myeloperoxidase are involved in the mechanisms of action of mud bath treatment [10].
• Mud bath therapy influences nitric oxide, myeloperoxidase and glutathione peroxidase serum levels in arthritic patients [10].

References