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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Glanders

 
 
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High impact information on Glanders

  • Doxycycline was the superior of the two antimicrobials against experimental glanders although relapse did occur in treated animals approximately 4-5 weeks after challenge [1].
  • The results presented here demonstrate that the capsular polysaccharide of B. mallei is required for production of disease in two animal models of glanders infection and is a major virulence factor [2].

References

  1. Comparison of efficacy of ciprofloxacin and doxycycline against experimental melioidosis and glanders. Russell, P., Eley, S.M., Ellis, J., Green, M., Bell, D.L., Kenny, D.J., Titball, R.W. J. Antimicrob. Chemother. (2000) [Pubmed]
  2. Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant. DeShazer, D., Waag, D.M., Fritz, D.L., Woods, D.E. Microb. Pathog. (2001) [Pubmed]
 
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