Disease relevance of Bone Marrow Cells

• Dihydrofluorouracil (FUH2), the initial catabolite of 5-fluorouracil (FUra), was examined to determine whether this derivative had antitumor activity or host cell (bone marrow) toxicity [1].

High impact information on Bone Marrow Cells

• In this study we used the 5T experimental mouse model to analyze the involvement of LFA-1 in myeloma cell bone marrow homing, survival, and growth [2].
• The combination of donor pretreatment with deoxyspergualin plus F1 bone-marrow-cell injection followed by post-operative deoxyspergualin administration, however, resulted in significant prolongation in recipient survival compared with control (26.1+/-1.7 days) [3].
• A hydroxyapatite chamber was molded into a cylindrical shape, and hydroxyapatite fillers were soaked in an autogenous bone-marrow-cell suspension at a concentration of 1.6 x 10(8)/ml [4].
• A factor which specifically inhibits the proliferation of murine bone-marrow-cell colonies in vitro was extracted from calf spleen and partially purified [5].

Associations of Bone Marrow Cells with chemical compounds

• Deoxyspergualin, when employed either alone as recipient post-treatment or as donor pretreatment, both with and without additional pretreatment with F1 recipient bone-marrow-cell injection, did not result in significant prolongation of recipient survival [3].

Analytical, diagnostic and therapeutic context of Bone Marrow Cells

• In this study, we investigated whether or not deoxyspergualin used as donor pretreatment, with and without pretreatment using bone-marrow-cell injection, could alleviate graft-versus-host reaction (GVHR) following small-bowel transplantation in an unidirectional GVHR model with Lewis (LEW)-to-F1 rats [3].

References