Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

MeSH Review:

Base Pair Mismatch

Otokiti, E.O. et al., Torigoe, H. et al., Chatake, T. et al., Li, Y. et al.

Torigoe, Kawahashi, Takamori, Ono,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Base Pair Mismatch

NMR and molecular modeling evidence for a G.A mismatch base pair in a purine-rich DNA duplex [1].
In a previous paper, 2'-deoxy-N(6)-methoxyadenosine (mo(6)A) was shown to form a mismatch base-pair with 2'-deoxycytidine with a Watson-Crick-type geometry [2].
The presence of a mismatch destabilizes a duplex relative to the perfect matched base pair duplex by 1.7-10.0 kcal/mol depending upon position of the mismatch, type of mismatch base pair involved, and Na+ concentration [3].
Novel strategy for single nucleotide polymorphism (SNP) genotyping by heteroduplex analysis: specific stabilization of TT mismatch base pair by mercury (II) cation and CC mismatch base pair by silver (I) cation [4].

References

NMR and molecular modeling evidence for a G.A mismatch base pair in a purine-rich DNA duplex. Li, Y., Zon, G., Wilson, W.D. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
Crystallographic studies on damaged DNAs. II. N(6)-methoxyadenine can present two alternate faces for Watson-Crick base-pairing, leading to pyrimidine transition mutagenesis. Chatake, T., Hikima, T., Ono, A., Ueno, Y., Matsuda, A., Takénaka, A. J. Mol. Biol. (1999) [Pubmed]
Effect of base pair A/C and G/T mismatches on the thermal stabilities of DNA oligomers that form B-Z junctions. Otokiti, E.O., Sheardy, R.D. Biochemistry (1997) [Pubmed]
Novel strategy for single nucleotide polymorphism (SNP) genotyping by heteroduplex analysis: specific stabilization of TT mismatch base pair by mercury (II) cation and CC mismatch base pair by silver (I) cation. Torigoe, H., Kawahashi, K., Takamori, A., Ono, A. Nucleosides Nucleotides Nucleic Acids (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share