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MeSH Review:

Alcohol Amnestic Disorder

St Clair, D.M. et al., Martin, P.R. et al., Emsley, R. et al., Martin, P.R. et al., Willenbring, M.L., et al.

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Psychiatry related information on Alcohol Amnestic Disorder

P3 and other long latency auditory evoked potentials in presenile dementia Alzheimer type and alcoholic Korsakoff syndrome [1].
Alcoholic dementia may be a more severe form of alcoholic Korsakoff syndrome, aetiologically related to the nutritionally-induced diencephalic pathology, rather than the neurotoxic effects of alcohol on the cortex [2].

High impact information on Alcohol Amnestic Disorder

In a 4-week double-blind crossover design, the serotonin-uptake blocker fluvoxamine maleate (100 to 200 mg/d) was found to improve episodic memory in only the patients with alcohol amnestic disorder [3].
Cerebrospinal fluid (CSF; n = 5) and plasma (n = 7) levels of norepinephrine (NE) and its major metabolite, 3-methoxy-4-hydroxyphenylglycol (MHPG) were examined in abstinent normotensive men with alcohol amnestic disorder during placebo and after 2 wk of clonidine treatment (6 or 12 micrograms/kg/day) [4].
Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder [5].
Paroxetine treatment in alcohol amnestic disorder [6].
Alcohol amnestic disorder seems to result from the synergistic combination of drinking, malnutrition, and genetic vulnerability to thiamine deficiency [7].

Chemical compound and disease context of Alcohol Amnestic Disorder

The P300 (P3) and other long latency auditory evoked potentials were measured in 15 patients with presenile dementia Alzheimer type (ATD), 16 patients with alcoholic Korsakoff syndrome (KS) and 23 age-matched control subjects [1].

References

P3 and other long latency auditory evoked potentials in presenile dementia Alzheimer type and alcoholic Korsakoff syndrome. St Clair, D.M., Blackwood, D.H., Christie, J.E. The British journal of psychiatry : the journal of mental science. (1985) [Pubmed]
Magnetic resonance imaging in alcoholic Korsakoff's syndrome: evidence for an association with alcoholic dementia. Emsley, R., Smith, R., Roberts, M., Kapnias, S., Pieters, H., Maritz, S. Alcohol Alcohol. (1996) [Pubmed]
Effective pharmacotherapy of alcoholic amnestic disorder with fluvoxamine. Preliminary findings. Martin, P.R., Adinoff, B., Eckardt, M.J., Stapleton, J.M., Bone, G.A., Rubinow, D.R., Lane, E.A., Linnoila, M. Arch. Gen. Psychiatry (1989) [Pubmed]
Effects of clonidine on central and peripheral catecholamine metabolism. Martin, P.R., Ebert, M.H., Gordon, E.K., Linnoila, M., Kopin, I.J. Clin. Pharmacol. Ther. (1984) [Pubmed]
Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder. Martin, P.R., Ebert, M.H., Gordon, E.K., Kopin, I.J. Clin. Pharmacol. Ther. (1983) [Pubmed]
Paroxetine treatment in alcohol amnestic disorder. Preuss, U.W., Soyka, M. The Journal of neuropsychiatry and clinical neurosciences. (1999) [Pubmed]
Organic mental disorders associated with heavy drinking and alcohol dependence. Willenbring, M.L. Clin. Geriatr. Med. (1988) [Pubmed]

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