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MeSH Review

Heart-Assist Devices

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High impact information on Heart-Assist Devices

  • A segmented polyether urethane was used as the blood contacting surface in a series of 10 heart assist devices implanted in calves for periods up to 35 weeks [1].
  • The artificial ventricle consists of a polycarbonate housing with an inlet and outlet polyurethane tricuspid valve [2].
  • Since 1988, 295 patients have undergone MCS at the German Heart Institute Berlin; 246 received biventricular support with the extracorporeal pneumatically-driven Berlin Heart Assist Device, 49 received left ventricular support with implantable assist devices (33 Novacor, 16 TCI) [3].
  • The internal coating of these artificial ventricles is made of a molded single-piece, glutaraldehyde-preserved pericardial sac [4].
  • The present study addressed the filling sensitivity and power output of the TOYOBO VAD (TVAD) and Utah soft artificial ventricle (USAV) to evaluate these pumps as a muscle powered cardiac assist device (MCAD) [5].

Associations of Heart-Assist Devices with chemical compounds


  1. Surface and bulk characteristics of a polyether urethane for artificial hearts. Boretos, J.W., Pierce, W.S., Baier, R.E., Leroy, A.F., Donachy, H.J. J. Biomed. Mater. Res. (1975) [Pubmed]
  2. A new pneumatic pump for extracorporeal circulation: TPP (true pulsatile pump). Experimental and first clinical results. Waldenberger, F.R., Vandezande, E., Janssens, P., Morishige, N., Demeyere, R., de Ruyter, E., Wiebalck, A., Flameng, W. The International journal of artificial organs. (1997) [Pubmed]
  3. Long-term mechanical circulatory support as a bridge to transplantation, for recovery from cardiomyopathy, and for permanent replacement. Loebe, M., Hennig, E., Müller, J., Spiegelsberger, S., Weng, Y., Hetzer, R. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. (1997) [Pubmed]
  4. Concept of totally biological internal coating for newly shaped artificial ventricles. Chatel, D. Artificial organs. (1996) [Pubmed]
  5. Ex vivo performance of muscle powered cardiac assist device: potential for right ventricular support. Sakakibara, N., Takemura, H., Tedoriya, T., Kawasuji, M., Misaki, T., Iwa, T. Journal of cardiac surgery. (1991) [Pubmed]
  6. In vitro evaluation of U.S. and U.S.S.R. artificial hearts. Guskov, I.A., Itkin, G.P., Lokshin, M.A., Shumakov, V.I., Chimoskey, J.E., O'Bannon, W., Walker, W.F., Lloyd, J.M., Noon, G.P., DeBakey, M.E. Artificial organs. (1982) [Pubmed]
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