Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Cardiovascular Diseases

Jones, E.S. et al., Sesso, H.D., van den Akker, E.L. et al.

Howard D. Sesso,

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Chemical compound and disease context of Cardiovascular Diseases

The promise of early epidemiological studies on carotenoids and cardiovascular disease paved the way to largely disappointing results from several large prevention trials of beta-carotene [1].
Our findings suggest that genetically determined cortisol sensitivity is involved in the pathogenesis of cardiovascular disease and might identify a subgroup at risk [2].
During cardiovascular disease, there is likely to be an increased functional importance of AT2R, stimulated by Ang II, or even shorter angiotensin peptide fragments, to limit AT1R-mediated overactivity and cardiovascular pathologies [3].

References

Carotenoids and cardiovascular disease: what research gaps remain? Sesso, H.D. Curr. Opin. Lipidol. (2006) [Pubmed]
Glucocorticoid receptor gene and risk of cardiovascular disease. van den Akker, E.L., Koper, J.W., van Rossum, E.F., Dekker, M.J., Russcher, H., de Jong, F.H., Uitterlinden, A.G., Hofman, A., Pols, H.A., Witteman, J.C., Lamberts, S.W. Arch. Intern. Med. (2008) [Pubmed]
AT2 receptors: functional relevance in cardiovascular disease. Jones, E.S., Vinh, A., McCarthy, C.A., Gaspari, T.A., Widdop, R.E. Pharmacol. Ther. (2008) [Pubmed]

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