Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Transduction, Genetic

Podrazik, R.M. et al., Abe, J. et al., Tomiyasu, K. et al., Abe, J. et al., Hanenberg, H. et al., et al.

Williams,

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Disease relevance of Transduction, Genetic

Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells [1].

High impact information on Transduction, Genetic

Successful genetic transduction of endothelial cells (EC) provides a theoretic means of increasing luminal secretion of tissue-type plasminogen activator (tPA) and lessening arterial and venous thrombotic processes [2].
Systemic loading of isoproterenol increased the cardiac parameters more significantly on day 2 to day 7, indicating that the adrenergic response was augmented by the genetic transduction [3].
In vivo antitumor effect of cytotoxic T lymphocytes engineered to produce interferon-gamma by adenovirus-mediated genetic transduction [4].
For the preparation of a GM-CSF gene-modified tumor vaccine, it is important to achieve efficient genetic transduction of tumor cells, leading to an appropriate expression of the induced gene [5].
Genetic transduction of hematopoietic stem cells via retroviral vectors has been hampered by low efficiency of gene transfer [6].

References

Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Hanenberg, H., Xiao, X.L., Dilloo, D., Hashino, K., Kato, I., Williams, D.A. Nat. Med. (1996) [Pubmed]
High-level expression of recombinant human tPA in cultivated canine endothelial cells under varying conditions of retroviral gene transfer. Podrazik, R.M., Whitehill, T.A., Ekhterae, D., Williams, W.D., Messina, L.M., Stanley, J.C. Ann. Surg. (1992) [Pubmed]
Direct intra-cardiomuscular transfer of beta2-adrenergic receptor gene augments cardiac output in cardiomyopathic hamsters. Tomiyasu, K., Oda, Y., Nomura, M., Satoh, E., Fushiki, S., Imanishi, J., Kondo, M., Mazda, O. Gene Ther. (2000) [Pubmed]
In vivo antitumor effect of cytotoxic T lymphocytes engineered to produce interferon-gamma by adenovirus-mediated genetic transduction. Abe, J., Wakimoto, H., Tsunoda, R., Okabe, S., Yoshida, Y., Aoyagi, M., Hirakawa, K., Hamada, H. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
Antitumor effect induced by granulocyte/macrophage-colony-stimulating factor gene-modified tumor vaccination: comparison of adenovirus- and retrovirus-mediated genetic transduction. Abe, J., Wakimoto, H., Yoshida, Y., Aoyagi, M., Hirakawa, K., Hamada, H. J. Cancer Res. Clin. Oncol. (1995) [Pubmed]
Retroviral-fibronectin interactions in transduction of mammalian cells. Williams, D.A. Ann. N. Y. Acad. Sci. (1999) [Pubmed]

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