Successful management of post-esophagectomy chylothorax/chyloperitoneum by etilefrine.
Post-operative chylothorax and chyloperitoneum resulting from a thoracic duct injury are possible complications of esophagectomy for carcinoma. Management of such conditions includes conservative methods (pleural drainage, chyle flow reduction and supportive nutrition) and surgery. Etilefrine, a sympathomimetic drug used in the management of postural hypotension, also causes smooth muscle contraction of the thoracic duct. We successfully treated three patients with post-esophagectomy chylothorax and chyloperitoneum using intravenous etilefrine. Etilefrine infusion allowed chyle flow resolution in a few days without any side-effects. As result of this experience, we believe that etilefrine deserves to be considered as an alternative therapy in the management of post-esophagectomy chylothorax/chyloperitoneum.[1]References
- Successful management of post-esophagectomy chylothorax/chyloperitoneum by etilefrine. Guillem, P., Billeret, V., Houcke, M.L., Triboulet, J.P. Dis. Esophagus (1999) [Pubmed]
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