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Chattopadhyay, S.K. et al.

Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material.

DNA of the AKR mouse contains a set of murine leukemia virus sequences that are not present in DNA of the NIH Swiss mouse. NIH mice partially congenic for the AKR murine-leukemia-virus- inducing locus Akv-1 contain this set of sequences, and, in a three-point cross segregating for Akv-1 on an NIH background, the sequences segregated with Akv-1. It is concluded that the Akv-1 locus contains viral sequences.[1]

References

Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material. Chattopadhyay, S.K., Rowe, W.P., Teich, N.M., Lowy, D.R. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]

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