- The tyrosine kinase NPM-ALK, associated with anaplastic large cell lymphoma, binds the intracellular domain of the surface receptor CD30 but is not activated by CD30 stimulation. Hübinger, G., Scheffrahn, I., Müller, E., Bai, R., Duyster, J., Morris, S.W., Schrezenmeier, H., Bergmann, L. Exp. Hematol. (1999)