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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Synthesis of biomimetic analogs of neomycin B: potential inhibitors of the HIV RNA Rev response element.

The aminoglycosidic antibiotic, neomycin B, is an inhibitor of the binding of Rev to RRE. This paper reports on the synthesis of analogs of neomycin B as potential anti-HIV compounds designed to function as inhibitors of Rev/RRE binding.[1]

References

  1. Synthesis of biomimetic analogs of neomycin B: potential inhibitors of the HIV RNA Rev response element. Nishizono, N., Nair, V. Nucleosides Nucleotides Nucleic Acids (2000) [Pubmed]
 
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