- High affinity binding between lipoprotein lipase and lipoproteins involves multiple ionic and hydrophobic interactions, does not require enzyme activity, and is modulated by glycosaminoglycans. Hussain, M.M., Obunike, J.C., Shaheen, A., Hussain, M.J., Shelness, G.S., Goldberg, I.J. J. Biol. Chem. (2000)