The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Poly(D,L-lactide/epsilon-caprolactone)/hydroxyapatite composites.

In this study, elastomeric D,L-lactide and epsilon-caprolactone copolymers with two different molecular weights (Mn: 108.000 and 40.000) were synthesized by ring-opening polymerization of the respective dimers by using stannous octoate as the catalyst, as a potential bone-filling material. The final ratio of D,L-lactide to epsilon-caprolactone obtained by 1NMR was 60/40 (comparing to the initial ratio of 50/50). Both copolymers were amorphous having Tg at around -21 degrees C. Different amounts of hydroxyapatite (HA) powder were loaded within the copolymers. These composites were easily shaped by hand. Mechanical properties of the composites changed with the HA loading and the molecular weight of the copolymer. The percent elongation decreased, while both the Young's modulus and yield point (stress) increased with the HA content. The copolymers were degraded within the Ringer solutions in about 6 weeks. The molecular weight distribution became broader during degradation. Incorporation of HA reduced the degradation rate.[1]


  1. Poly(D,L-lactide/epsilon-caprolactone)/hydroxyapatite composites. Ural, E., Kesenci, K., Fambri, L., Migliaresi, C., Piskin, E. Biomaterials (2000) [Pubmed]
WikiGenes - Universities