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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Impact of flavophospholipol and vancomycin on conjugational transfer of vancomycin resistance plasmids.

The influence of vancomycin and flavophospholipol (FPL) on the transfer rate of conjugative plasmids harboring the vancomycin resistance operon vanA was determined in several clinical and animal isolates of Enterococcus faecium. FPL significantly inhibited the frequency of transfer of conjugative VanA plasmids up to 70-fold. Vancomycin had no significant effect on the transfer rate of VanA plasmids.[1]

References

  1. Impact of flavophospholipol and vancomycin on conjugational transfer of vancomycin resistance plasmids. Riedl, S., Ohlsen, K., Werner, G., Witte, W., Hacker, J. Antimicrob. Agents Chemother. (2000) [Pubmed]
 
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