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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Common chromosome aberrations in the proximal type of epithelioid sarcoma.

A new case of the proximal type of epithelioid sarcoma with a complex karyotype 70-98 <4N>,XX,-X,-X,+5,i(5)(q10),+7,del(7)(q31),i(8)(q10)x3 approximately 4,del(12)(p13),der(18)ins(18:?) (q11;?)del(18)(p11). ish der(18)ins(18;X)del(18)(p11)(wcp18+,wcpX+),+20,+20,dmin [cp9] is described. Both, dual-color FISH using probes specific for OATLI1/OATL2 genes and RT-PCR analysis excluded the presence of t(X;18), typical for synovial sarcoma. Our case together with the previously published ones suggest that the presence of i(8)(q10), losses of 12p and 18p together with the gain of chromosome 20 may represent a common cytogenetic aberrations in the proximal type of epithelioid sarcoma.[1]

References

  1. Common chromosome aberrations in the proximal type of epithelioid sarcoma. Debiec-Rychter, M., Sciot, R., Hagemeijer, A. Cancer Genet. Cytogenet. (2000) [Pubmed]
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