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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Basilar artery thrombosis in a child heterozygous for factor V Leiden mutation.

Activated protein C resistance, usually because of factor V Leiden mutation, is considered to be the most common hereditary prothrombotic condition. A 9-year-old male with a basilar artery stroke and activated protein C resistance is described. The patient, found to be heterozygous for factor V Leiden mutation, is one of several recent reports that suggest that activated protein C resistance is an important risk factor for spontaneous arterial thrombosis in infancy and childhood.[1]

References

  1. Basilar artery thrombosis in a child heterozygous for factor V Leiden mutation. Verdú, A., Cazorla, M.R., Granados, M.A., Alonso, J.A., Casado, L.F. Pediatric neurology. (2001) [Pubmed]
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