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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Social impact of nasopharyngeal carcinoma on Chinese households in Selangor, Malaysia.

AIM OF STUDY: With a five-year survival rate of 20% in 1970 and 40-45% in 1990, and highest incidence and mortality in early and middle adult years, nasopharyngeal carcinoma ( NPC) may have a severe social impact on families and households. The aim of this study was to measure the social impact of NPC in the Chinese population of Selangor, Malaysia. METHOD: Cases were pooled from three epidemiological case-control studies conducted in 1973-74, 1980, and 1990-92 for a total of 442. They lived in households with a grand total of 2,598 persons. Interviewers collected data on household composition: number of residents; each resident's age, sex, occupation, and relationship to the head of the household; and position of the NPC case in the household. RESULTS: Ninety-four percent of cases supported 93% of household members in some way. Most cases were employed as income earners or homemakers and 80% had a key role as head of household and/or parent of dependent children. CONCLUSION: The illness and death caused by NPC had a major social impact on immediate families and on extended family and non-kin households as well.[1]


  1. Social impact of nasopharyngeal carcinoma on Chinese households in Selangor, Malaysia. Armstrong, R.W., Armstrong, M.J., Lye, M.S. Singapore medical journal. (2000) [Pubmed]
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