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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Case-Control Studies

 
 
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Disease relevance of Case-Control Studies

 

Psychiatry related information on Case-Control Studies

 

High impact information on Case-Control Studies

  • METHODS: We conducted a population-based case-control study of ovarian cancer among Jewish women in Israel. Women were tested for the two founder mutations in BRCA1 and the one founder mutation in BRCA2 that are known to be common among Jews [11].
  • In three of four independent case-control studies, we demonstrated an association of the mutation with MS [12].
  • The OCT-1-binding genotype, found in approximately 5% of Africans, is associated with fourfold increased susceptibility to cerebral malaria in large case-control studies of West African and East African populations, after correction for other known TNF polymorphisms and linked HLA alleles [13].
  • METHODS: Case-control studies were performed at three of the four hospitals to assess the relation of the use of clindamycin to C. difficile-associated diarrhea [14].
  • We conducted a case-control study, using medical-history reviews, serologic testing, and testing with the polymerase chain reaction for E. chaffeensis infection [15].
 

Chemical compound and disease context of Case-Control Studies

 

Biological context of Case-Control Studies

 

Anatomical context of Case-Control Studies

 

Associations of Case-Control Studies with chemical compounds

  • A case-control study based on toxicologic analyses of postmortem blood samples indicates that concentrations of both heroin and ethanol are substantial risk factors for heroin-related deaths [31].
  • We performed a case-control study looking at thiazide use and subsequent hip fracture in postmenopausal female members of the Framingham Study cohort [32].
  • DESIGN AND SETTING: Prospective, nested case-control study in the Cholesterol and Recurrent Events (CARE) trial, a randomized placebo-controlled trial of pravastatin conducted in 1989-1996 [33].
  • The relationship between truck driving and bladder cancer mortality was investigated in a case-control study in New Hampshire and Vermont. In-person interviews were conducted with the next-of-kin of 325 bladder cancer cases and 673 controls who died during 1975-79 [34].
  • In the nested case-control study, HBV carriers in the highest tertile of testosterone levels had a statistically significantly increased risk of HCC (OR = 2.06; 95% CI = 1.14--3.70) compared with those in the lowest tertile [35].
 

Gene context of Case-Control Studies

 

Analytical, diagnostic and therapeutic context of Case-Control Studies

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