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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Anti-proliferative effect of two lactic acid bacteria strains of human origin on the growth of a myeloma cell line.

AIMS: Twenty lactic acid bacteria strains were isolated from human faeces and tested by MTT assay for stimulation or inhibition of the proliferation of Vero and myeloma cells. METHODS AND RESULTS: None of the strains significantly affected the proliferation of Vero cells. However, two isolates ( HN1 and HA8) showed a strong inhibition of myeloma cell proliferation (16.7 and 5.0%, respectively) by MTT assay. CONCLUSION: Both strains have an anti-proliferative effect on a tumoral cell line. SIGNIFICANCE AND IMPACT OF THE STUDY: The beneficial effect of LAB cancer therapy has been linked to their ability for immunomodulation.[1]

References

  1. Anti-proliferative effect of two lactic acid bacteria strains of human origin on the growth of a myeloma cell line. Zabala, A., Martín, M.R., Haza, A.I., Fernández, L., Rodríguez, J.M., Morales, P. Lett. Appl. Microbiol. (2001) [Pubmed]
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