- Shy1p occurs in a high molecular weight complex and is required for efficient assembly of cytochrome c oxidase in yeast. Nijtmans, L.G., Artal Sanz, M., Bucko, M., Farhoud, M.H., Feenstra, M., Hakkaart, G.A., Zeviani, M., Grivell, L.A. FEBS Lett. (2001)