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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Measurement of allergenic potency using the local lymph node assay.

Chemicals that can act as contact allergens have been identified successfully using guinea-pig models. However, contact allergy is still common, probably because of, at least in part, failures of risk assessment. A new method, the local lymph node assay, replaces the guinea-pig as a tool for hazard identification and offers the real prospect of accurate prediction of allergen potency, the missing link in skin sensitization risk assessment.[1]

References

  1. Measurement of allergenic potency using the local lymph node assay. Basketter, D.A., Gerberick, G.F., Kimber, I. Trends Pharmacol. Sci. (2001) [Pubmed]
 
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