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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Investigations on antibacterial activity of cefazedone against Neisseria gonorrhoeae.

The sensitivity of 67 strains of Neisseria gonorrhoeae isolated from 1977 to 1978 were tested against the new cephalosporin derivative (6R,7R)-7-(2-[3,5-dichloro-4-oxo-1(4H)-pyridyl]-acetamido)-3-([(5-methyl-1,3,4-thiadiazol-2-yl)-thio]methyl)-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid (cefazedone, Refosporen). All strains including three penicillin-resistant beta-lactamase producing Neisseria were sensitive at a range of 0.0078 to 2.0 micrograms/ml cefazedone.[1]

References

  1. Investigations on antibacterial activity of cefazedone against Neisseria gonorrhoeae. Gründer, K., Petzoldt, D. Arzneimittel-Forschung. (1979) [Pubmed]
 
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