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Chemical Compound Review

AC1L1U4I     (6S,7R)-3-(acetyloxymethyl)- 7-[(5-amino-5...

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Disease relevance of CEPHALOSPORIN


Psychiatry related information on CEPHALOSPORIN


High impact information on CEPHALOSPORIN


Chemical compound and disease context of CEPHALOSPORIN


Biological context of CEPHALOSPORIN


Anatomical context of CEPHALOSPORIN


Associations of CEPHALOSPORIN with other chemical compounds


Gene context of CEPHALOSPORIN


Analytical, diagnostic and therapeutic context of CEPHALOSPORIN


  1. Resistance to penicillin and cephalosporin and mortality from severe pneumococcal pneumonia in Barcelona, Spain. Pallares, R., Liñares, J., Vadillo, M., Cabellos, C., Manresa, F., Viladrich, P.F., Martin, R., Gudiol, F. N. Engl. J. Med. (1995) [Pubmed]
  2. Molecular regulation of beta-lactam biosynthesis in filamentous fungi. Brakhage, A.A. Microbiol. Mol. Biol. Rev. (1998) [Pubmed]
  3. Designing appropriate therapy in the treatment of gram-negative bacillary meningitis. Corrado, M.L., Gombert, M.E., Cherubin, C.E. JAMA (1982) [Pubmed]
  4. Recurrent urinary tract infections. Prevention by prophylactic antibiotics after sexual intercourse. Vosti, K.L. JAMA (1975) [Pubmed]
  5. Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure. Martínez-Rodríguez, J.E., Barriga, F.J., Santamaria, J., Iranzo, A., Pareja, J.A., Revilla, M., dela Rosa, C.R. Am. J. Med. (2001) [Pubmed]
  6. Drug usage review and inventory analysis in promoting rational parenteral cephalosporin therapy. Simon, W.A., Thompson, L., Campbell, S., Lantos, R.L. American journal of hospital pharmacy. (1975) [Pubmed]
  7. Cost, motion, and time studies comparing a new cephalosporin admixture system. Turco, S.J. Hospital pharmacy. (1982) [Pubmed]
  8. Microbial sensor for new-generation cephalosporins based in a protein-engineered beta-lactamase. García, J.L., Nuñez, C.J., González, E.G., Osuna, J., Soberón, X., Galindo, E. Appl. Biochem. Biotechnol. (1998) [Pubmed]
  9. Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution. Navia, M.A., Springer, J.P., Lin, T.Y., Williams, H.R., Firestone, R.A., Pisano, J.M., Doherty, J.B., Finke, P.E., Hoogsteen, K. Nature (1987) [Pubmed]
  10. Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase. Doherty, J.B., Ashe, B.M., Argenbright, L.W., Barker, P.L., Bonney, R.J., Chandler, G.O., Dahlgren, M.E., Dorn, C.P., Finke, P.E., Firestone, R.A. Nature (1986) [Pubmed]
  11. Pseudomembranous colitis associated with single-dose cephalosporin prophylaxis. Freiman, J.P., Graham, D.J., Green, L. JAMA (1989) [Pubmed]
  12. Antimicrobial vs placebo prophylaxis in noncardiac thoracic surgery. Truesdale, R., D'Alessandri, R., Manuel, V., Daicoff, G., Kluge, R.M. JAMA (1979) [Pubmed]
  13. Transferable cephalosporin resistance not inhibited by clavulanate in Escherichia coli. Woodford, N., Payne, D.J., Johnson, A.P., Weinbren, M.J., Perinpanayagam, R.M., George, R.C., Cookson, B.D., Amyes, S.G. Lancet (1990) [Pubmed]
  14. A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis. Lee, W., McDonough, M.A., Kotra, L., Li, Z.H., Silvaggi, N.R., Takeda, Y., Kelly, J.A., Mobashery, S. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  15. In vitro and in vivo activities of a doxorubicin prodrug in combination with monoclonal antibody beta-lactamase conjugates. Svensson, H.P., Vrudhula, V.M., Emswiler, J.E., MacMaster, J.F., Cosand, W.L., Senter, P.D., Wallace, P.M. Cancer Res. (1995) [Pubmed]
  16. Antibiotic treatment of infective endocarditis. Wilson, W.R., Geraci, J.E. Annu. Rev. Med. (1983) [Pubmed]
  17. Mutations affecting the catalytic activity of Bacillus cereus 5/B/6 beta-lactamase II. Lim, H.M., Pène, J.J. J. Biol. Chem. (1989) [Pubmed]
  18. Chemical complementation: a reaction-independent genetic assay for enzyme catalysis. Baker, K., Bleczinski, C., Lin, H., Salazar-Jimenez, G., Sengupta, D., Krane, S., Cornish, V.W. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  19. Pre-steady state beta-lactamase kinetics. Observation of a covalent intermediate during turnover of a fluorescent cephalosporin by the beta-lactamase of STaphylococcus aureus PC1. Anderson, E.G., Pratt, R.F. J. Biol. Chem. (1981) [Pubmed]
  20. Altering the substrate specificity of cephalosporin acylase by directed evolution of the Beta -subunit. Otten, L.G., Sio, C.F., Vrielink, J., Cool, R.H., Quax, W.J. J. Biol. Chem. (2002) [Pubmed]
  21. Amino acid sequence determinants of extended spectrum cephalosporin hydrolysis by the class C P99 beta-lactamase. Zhang, Z., Yu, Y., Musser, J.M., Palzkill, T. J. Biol. Chem. (2001) [Pubmed]
  22. Active site residues of cephalosporin acylase are critical not only for enzymatic catalysis but also for post-translational modification. Kim, S., Kim, Y. J. Biol. Chem. (2001) [Pubmed]
  23. Pathogenesis of ceftriaxone-associated biliary sludge. In vitro studies of calcium-ceftriaxone binding and solubility. Shiffman, M.L., Keith, F.B., Moore, E.W. Gastroenterology (1990) [Pubmed]
  24. Successful treatment of gram-negative bacillary meningitis with moxalactam. Olson, D.A., Hoeprich, P.D., Nolan, S.M., Goldstein, E. Ann. Intern. Med. (1981) [Pubmed]
  25. Detection of extracellular neutrophil elastase in hamster lungs after intratracheal instillation of E. coli lipopolysaccharide using a fluorogenic, elastase-specific, synthetic substrate. Rudolphus, A., Stolk, J., van Twisk, C., van Noorden, C.J., Dijkman, J.H., Kramps, J.A. Am. J. Pathol. (1992) [Pubmed]
  26. Cephalosporin-sensitive penicillin-binding proteins of Staphylococcus aureus and Bacillus subtilis active in the conversion of [14C]penicillin G to [14C]phenylacetylglycine. Waxman, D.J., Strominger, J.L. J. Biol. Chem. (1979) [Pubmed]
  27. Cefdinir (CI-983), a new oral amino-2-thiazolyl cephalosporin, inhibits human neutrophil myeloperoxidase in the extracellular medium but not the phagolysosome. Labro, M.T., el Benna, J., Charlier, N., Abdelghaffar, H., Hakim, J. J. Immunol. (1994) [Pubmed]
  28. Cephalosporin-induced alteration in hepatic glutathione redox state. A potential mechanism for inhibition of hepatic reduction of vitamin K1,2,3-epoxide in the rat. Mitchell, M.C., Mallat, A., Lipsky, J.J. J. Clin. Invest. (1990) [Pubmed]
  29. Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin. Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H. J. Biol. Chem. (2002) [Pubmed]
  30. Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase. Spencer, J., Clarke, A.R., Walsh, T.R. J. Biol. Chem. (2001) [Pubmed]
  31. Role of the omega-loop in the activity, substrate specificity, and structure of class A beta-lactamase. Banerjee, S., Pieper, U., Kapadia, G., Pannell, L.K., Herzberg, O. Biochemistry (1998) [Pubmed]
  32. Mechanism of tonB-dependent transport of KP-736, a 1,5-dihydroxy-4-pyridone-substituted cephalosporin, into Escherichia coli K-12 cells. Tatsumi, Y., Maejima, T., Mitsuhashi, S. Antimicrob. Agents Chemother. (1995) [Pubmed]
  33. Epidemiology of plasmid-mediated beta-lactamases in enterobacteria Swedish neonatal wards and relation to antimicrobial therapy. Burman, L.G., Haeggman, S., Kuistila, M., Tullus, K., Huovinen, P. Antimicrob. Agents Chemother. (1992) [Pubmed]
  34. Cefaclor, a cephalosporin antibiotic, delays gastric emptying rate by a CCK-A receptor-mediated mechanism in the rat. Bozkurt, A., Deniz, M., Yegen, B.C. Br. J. Pharmacol. (2000) [Pubmed]
  35. Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 beta-lactamase. Doucet, N., De Wals, P.Y., Pelletier, J.N. J. Biol. Chem. (2004) [Pubmed]
  36. Health and economic outcomes of the emergence of third-generation cephalosporin resistance in Enterobacter species. Cosgrove, S.E., Kaye, K.S., Eliopoulous, G.M., Carmeli, Y. Arch. Intern. Med. (2002) [Pubmed]
  37. Cephalosporins as risk factor for nosocomial Enterococcus faecalis bacteremia. A matched case-control study. Pallares, R., Pujol, M., Peña, C., Ariza, J., Martin, R., Gudiol, F. Arch. Intern. Med. (1993) [Pubmed]
  38. The role of "colonization pressure" in the spread of vancomycin-resistant enterococci: an important infection control variable. Bonten, M.J., Slaughter, S., Ambergen, A.W., Hayden, M.K., van Voorhis, J., Nathan, C., Weinstein, R.A. Arch. Intern. Med. (1998) [Pubmed]
  39. Listeria monocytogenes septic arthritis. A case report and review of the literature. Curosh, N.A., Perednia, D.A. Arch. Intern. Med. (1989) [Pubmed]
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