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Costa, S.M. et al.

Chemical constituents from Lippia sidoides and cytotoxic activity.

Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone (13), were isolated from ethanol extracts of Lippia sidoides. Their structures were established by a combination of 1D and 2D NMR, IR, and EIMS spectral data analysis. The cytotoxic properties of compounds 3--13 were evaluated against HL60, SW1573, and CEM cell lines. Only tectol (6) and lippsidoquinone (13) exhibited significant activity against human leukemia cell lines HL60 and CEM.[1]

References

Chemical constituents from Lippia sidoides and cytotoxic activity. Costa, S.M., Lemos, T.L., Pessoa, O.D., Pessoa, C., Montenegro, R.C., Braz-Filho, R. J. Nat. Prod. (2001) [Pubmed]

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