Disease relevance of Lippia

• Agrobacterium tumefaciens strains containing nopaline tumor-inducing plasmids, A. tumefaciens Lippia isolates, and Agrobacterium rhizogenes strains produced trans-zeatin in culture at 0.5 to 44 micrograms/liter [1].
• T. usneoides dichloromethane, ethyl acetate and n-butanol extracts, and Lippia alba n-butanol extract showed inhibition of HSV-1, strain 29R/acyclovir resistant [2].

High impact information on Lippia

• Lippia dulcis Trev., a sweet plant, emerged as a candidate for fractionation studies, and hernandulcin, a sesquiterpene, was isolated and judged by a human taste panel as more than 1000 times sweeter than sucrose [3].
• The AB2/73 T-DNA sequence (3,504 bp) is flanked by canonical border sequences, has no detectable DNA homology with other T-DNAs, and contains only two genes: lsn (Lippia strain nopaline synthaselike gene) and lso (Lippia strain oncogene) [4].
• Comparison of different extraction methods for the analysis of volatile secondary metabolites of Lippia alba (Mill.) N.E. Brown, grown in Colombia, and evaluation of its in vitro antioxidant activity [5].
• Muscle relaxant properties of aqueous extract of Lippia multiflora [6].
• In a previous work, we found that Lippia beriandieri (Oregano) revealed to be more potent than tinidazole, a common antigiardiasic drug [7].

Associations of Lippia with chemical compounds

• Linalool from Lippia alba: study of the reproducibility of the essential oil profile and the enantiomeric purity [8].
• The effects of the total phenolic extract (TPLi) from Lippia multiflora leaves and of its 2 main components i.e. Verbascoside (VLi) and Lil on TXA2 biosynthesis were studied [9].
• From the leaves and flowers of Lippia dulcis collected in Panama, a new sweet sesquiterpene identified as (+)-4 beta-hydroxyhernandulcin [2] was isolated, accompanied by (+)-hernandulcin [1], (-)-epihernandulcin [3] (a novel natural product), and 6-methyl-5-hepten-2-one [4] [10].
• Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone (13), were isolated from ethanol extracts of Lippia sidoides [11].
• A 20% v/v preparation of lippia oil applied to scabietic subjects for 5 consecutive days gave 100% cure compared with 87.5% cure obtained for benzyl benzoate preparation of the same concentration [12].

Gene context of Lippia

• Three new compounds from the plant Lippia alva as inhibitors of chemokine receptor 5 (CCR5) [13].
• Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) n.e. Brown [14].
• Lippia alba (Mill.) N [15].
• The 'knockdown' times obtained for bodylice and headlice using lippia oil preparations were comparatively shorter than those obtained using benzyl benzoate and Delvap Super, a brand of dichlorvos [12].

References