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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The effect of 2,5,2',5'-tetrachlorobiphenyl on growth and death of the cyanobacterium Anabaena flos-aquae.

The effect of 2,5,2',5'-tetrachlorobiphenyl (TcBP) on cell death was investigated in the cyanobacterium Anabaena flos-aquae (Lyngb.) Bréb grown in a P-limited, semicontinuous culture under N2-fixing conditions during a 17-d period. The TcBP was supplied daily to yield final concentrations of 1, 10, and 100 ppb (or ng/ml). At 1 and 10 ppb, the population size of live cells (sum of live vegetative cells and live heterocysts) was not different from that of the TcBP-free controls (p > 0.1, t test) and remained constant both in its absolute value (9.6 X 10(5) cells/ml) and as a percentage of the total population (98.6%). However, at 100 ppb, the population size of live cells declined significantly after the 11th day (8.2 x 10(5) cells/ml, or 96.6% of total population; p < 0.01, t test). The decrease in viable cells was mostly found in vegetative cells. Bioconcentration factor in the cell ([pg TcBP/g dry wt cells]/[pg TcBP/ml]) was 1.23 x 10(5).[1]


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