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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Determination of difloxacin and sarafloxacin in chicken muscle using solid-phase extraction and capillary electrophoresis.

This paper describes a method for residue analysis of difloxacin and sarafloxacin in chicken muscle. Clean-up and preconcentration of the samples are effected by solid-phase extraction (C18) and the determination is carried out by capillary electrophoresis using a photodiode array detection system. The method was validated with satisfying results. The calibration graphs are linear for difloxacin and sarafloxacin from 50 to 300 microg/kg. The limit of detection obtained for difloxacin and sarafloxacin are 10 and 25 microg/kg, respectively, which allows the detection of positive muscle samples at the required maximum residue limits of European Union.[1]

References

  1. Determination of difloxacin and sarafloxacin in chicken muscle using solid-phase extraction and capillary electrophoresis. Barrón, D., Jiménez-Lozano, E., Bailac, S., Barbosa, J. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2002) [Pubmed]
 
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