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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Misidentification of a genomovar of Burkholderia cepacia by recA restriction fragment length polymorphism.

An 8 year old girl with cystic fibrosis presented with a pulmonary exacerbation from which Burkholderia cepacia was cultured. Subsequent polymerase chain reaction restriction fragment length polymorphism analysis of the recA gene suggested the presence of B cepacia Genomovar V (Burkholderia vietnamiensis); however, on subsequent sequence typing, this isolate was confirmed as B cepacia Genomovar IIIb. This report outlines the potential difficulties in the correct characterisation of the various genomovars within the B cepacia complex of organisms, which has particularly important implications for patient segregation and infection control.[1]

References

  1. Misidentification of a genomovar of Burkholderia cepacia by recA restriction fragment length polymorphism. Moore, J.E., Millar, B.C., Xu, J., Crowe, M., Redmond, A.O., Elborn, J.S. J. Clin. Pathol. (2002) [Pubmed]
 
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