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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The relationship between serum relaxin and knee joint laxity in female athletes.

Gravidity studies have intimated a relationship between serum relaxin levels and joint laxity. To assess its applicability to eumenorrheic athletes, weekly serum relaxin and knee arthrometry measurements were obtained in 57 collegiate women and 5 men for 4 consecutive weeks. The former included athletes, ACL-injured athletes, and nonathletes, while the latter formed an a priori hormonal control. Analysis of variance revealed a significant change in weekly serum relaxin levels in females but not in anterior translation. Regression analysis failed to disclose a relationship between these variables. Therefore, we conclude relaxin does not affect knee laxity.[1]


  1. The relationship between serum relaxin and knee joint laxity in female athletes. Arnold, C., Van Bell, C., Rogers, V., Cooney, T. Orthopedics. (2002) [Pubmed]
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