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Disease relevance of Gravidity


High impact information on Gravidity

  • Fetal loss rates were increased among couples sharing HLA-B as compared with couples not sharing HLA-B (.23 vs. .12, respectively; P = .041, adjusted for age, gravidity, and kinship) [6].
  • Gravidity and tubal disease also had marginal effects on the time course of inhibin responses, but not on overall mean inhibin levels or estradiol responses [7].
  • In order to determine the normal periprandial blood glucose values during gravidity, we studied 17 normal pregnant women, near term of gestation, in their homes using test strips and reflectometers . Results show an initial fasting level not higher than 80 mg/dl and not lower than 45 mg/dl [8].
  • The number of previous pregnancies (gravidity) was associated with stronger maternal responses to fetal alloantigens, as shown by lymphoproliferation (Kendall tau=0.3, P=0.04) and IFN-gamma (tau=0.3, P=0.04) synthesis, but did not affect fetal responses to the various stimuli [9].
  • Progesterone and gravidity differentially regulate expression of extracellular matrix components in the pregnant rat myometrium [10].

Chemical compound and disease context of Gravidity


Biological context of Gravidity


Anatomical context of Gravidity

  • To control for embryo quality, IVF patient characteristics were matched to those of the oocyte donors with regard to age and previous gravidity [15].
  • The following parameters were determined in colostrum taken from sows after completed delivery: specific gravidity; total proteins, lysozyme activity, IgG level [16].
  • The first immunopositive neuroblasts occurred in the 15th week of gravidity, whereas an increasing number of structures in the medulla oblongata and cerebellum showed ODC immunoreactivity in weeks 18-24 of gravidity [17].

Associations of Gravidity with chemical compounds


Gene context of Gravidity

  • CA-125 levels were independent of age, gravidity, weeks of amenorrhea, or presence of thecal-luteal cysts [23].
  • Patients in both groups were similar with respect to mean gravidity, parity, and menopausal status, although patients in the Novak group were older (43.4 vs 39.1 years, p = 0.005) [24].
  • The relative risk of hepatocellular carcinoma was elevated significantly in women of high gravidity, an association that was attributable to the effects of full-term pregnancies [25].
  • We have shown that gravidity and parity is associated with a small but progressive decrease in fetal NT and a small but progressive increase in free beta-hCG and PAPP-A [26].
  • Women with endometriosis and tubal inflammatory disease did not have a significantly lower mean gravidity than did those with healthy tubes [27].

Analytical, diagnostic and therapeutic context of Gravidity


  1. Gravidity, obesity, and non-insulin-dependent diabetes among Pima Indian women. Charles, M.A., Pettitt, D.J., McCance, D.R., Hanson, R.L., Bennett, P.H., Knowler, W.C. Am. J. Med. (1994) [Pubmed]
  2. Clinical and parasitological characteristics of puerperal malaria. Ramharter, M., Grobusch, M.P., Kiessling, G., Adegnika, A.A., Möller, U., Agnandji, S.T., Kramer, M., Schwarz, N., Kun, J.F., Oyakhirome, S., Issifou, S., Borrmann, S., Lell, B., Mordmüller, B., Kremsner, P.G. J. Infect. Dis. (2005) [Pubmed]
  3. Fetal growth and moderate drinking in early pregnancy. Little, R.E., Asker, R.L., Sampson, P.D., Renwick, J.H. Am. J. Epidemiol. (1986) [Pubmed]
  4. Oxidative stress and endometriosis. Jackson, L.W., Schisterman, E.F., Dey-Rao, R., Browne, R., Armstrong, D. Hum. Reprod. (2005) [Pubmed]
  5. Complete hydatidiform mole and surviving coexistent twin. Bristow, R.E., Shumway, J.B., Khouzami, A.N., Witter, F.R. Obstetrical & gynecological survey. (1996) [Pubmed]
  6. Decreased fecundability in Hutterite couples sharing HLA-DR. Ober, C., Elias, S., Kostyu, D.D., Hauck, W.W. Am. J. Hum. Genet. (1992) [Pubmed]
  7. Inhibin and estradiol responses to ovarian hyperstimulation: effects of age and predictive value for in vitro fertilization outcome. Hughes, E.G., Robertson, D.M., Handelsman, D.J., Hayward, S., Healy, D.L., de Kretser, D.M. J. Clin. Endocrinol. Metab. (1990) [Pubmed]
  8. Periprandial blood glucose and insulin values during the third trimester of normal pregnancies. Espinosa de los Monteros, A.M., Duarte, M.C., Quijano, J.V., Casanueva, E.L. Diabetes Care (1984) [Pubmed]
  9. Maternal reactivity to fetal alloantigens is related to newborn immune responses and subsequent allergic disease. Prescott, S.L., Taylor, A., Roper, J., Wahdan, A., Noakes, P., Thornton, C., Dunstan, J., Upham, J.W. Clin. Exp. Allergy (2005) [Pubmed]
  10. Progesterone and gravidity differentially regulate expression of extracellular matrix components in the pregnant rat myometrium. Shynlova, O., Mitchell, J.A., Tsampalieros, A., Langille, B.L., Lye, S.J. Biol. Reprod. (2004) [Pubmed]
  11. Preterm premature rupture of membranes: comparison between twin and singleton gestations. Myles, T.D., Espinoza, R., Meyer, W., Bieniarz, A. The Journal of maternal-fetal medicine. (1997) [Pubmed]
  12. Experimental cancer prophylaxis. Wrba, H. Experimental pathology. (1983) [Pubmed]
  13. Nomograms of sonographic measurements throughout gestation of the fetal hard palate width, length and area. Sherer, D.M., Sokolovski, M., Santoso, P.G., Dalloul, M., Abulafia, O. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. (2004) [Pubmed]
  14. Effect of captivity in semi-natural enclosures on the reproductive endocrinology of female lizards. Weiss, S.L., Jennings, D.H., Moore, M.C. Gen. Comp. Endocrinol. (2002) [Pubmed]
  15. Embryo implantation after human in vitro fertilization: importance of endometrial receptivity. Paulson, R.J., Sauer, M.V., Lobo, R.A. Fertil. Steril. (1990) [Pubmed]
  16. The influence of nonspecific immunostimulation of pregnant sows on the immunological value of colostrum. Krakowski, L., Krzyzanowski, J., Wrona, Z., Kostro, K., Siwicki, A.K. Vet. Immunol. Immunopathol. (2002) [Pubmed]
  17. Immunohistochemical demonstration of L-ornithine decarboxylase enzyme protein in different areas of the developing human brain. Müller, M., Pajunen, A.E., Järvinen, M., Poeggel, G., Bernstein, H.G. Dev. Neurosci. (1993) [Pubmed]
  18. Cocaine use and preterm premature rupture of membranes: improvement in neonatal outcome. Refuerzo, J.S., Sokol, R.J., Blackwell, S.C., Berry, S.M., Janisse, J.J., Sorokin, Y. Am. J. Obstet. Gynecol. (2002) [Pubmed]
  19. A comparison of oral prostaglandin E2 and intravenous oxytocin for induction of labor in normal and high-risk pregnancies. Nelson, G.H., Bryans, C.I. Am. J. Obstet. Gynecol. (1976) [Pubmed]
  20. Plasma C-21 steroids in conscious pregnant and non-pregnant rabbits with chronic catheterization of the femoral artery and the portal and hepatic veins. Nahoul, K., Gilbert, M. J. Steroid Biochem. Mol. Biol. (1991) [Pubmed]
  21. Postpartum contraceptive use among adolescent mothers. Templeman, C.L., Cook, V., Goldsmith, L.J., Powell, J., Hertweck, S.P. Obstetrics and gynecology. (2000) [Pubmed]
  22. Low-dose prostaglandin E2 analogue for cervical dilatation prior to pregnancy termination. Borten, M., DiLeo, L.A., Friedman, E.A. Am. J. Obstet. Gynecol. (1984) [Pubmed]
  23. CA-125: a marker for persistent gestational trophoblastic disease? Koonings, P.P., Schalerth, J.B. Gynecol. Oncol. (1993) [Pubmed]
  24. A prospective, randomized comparison of the Pipelle endometrial sampling device with the Novak curette. Stovall, T.G., Ling, F.W., Morgan, P.L. Am. J. Obstet. Gynecol. (1991) [Pubmed]
  25. Reproductive factors in the etiology of hepatocellular carcinoma. The WHO Collaborative Study of Neoplasia and Steroid Contraceptives. Stanford, J.L., Thomas, D.B. Cancer Causes Control (1992) [Pubmed]
  26. The influence of parity and gravidity on first trimester markers of chromosomal abnormality. Spencer, K., Ong, C.Y., Liao, A.W., Nicolaides, K.H. Prenat. Diagn. (2000) [Pubmed]
  27. Pelvic endometriosis and tubal inflammatory disease. Forrest, J., Buckley, C.H., Fox, H. Int. J. Gynecol. Pathol. (1984) [Pubmed]
  28. Direct and indirect interactions of cocaine with childbirth outcomes. Singer, L., Arendt, R., Song, L.Y., Warshawsky, E., Kliegman, R. Archives of pediatrics & adolescent medicine. (1994) [Pubmed]
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