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Overlapping and specific patterns of GDNF, c-ret and GFR alpha mRNA expression in the developing chicken retina.

GDNF and the GDNF receptors, c-Ret, GFR alpha 1 and 2 mRNA is expressed in the developing chicken retina. GDNF labelling was mainly found in embryonic day 4-5 retina but weak labelling could also be found over scattered retinal cells at later stages. c-ret labelling was found over ganglion cells, amacrine and horizontal cells; the preferred GDNF receptor (GFR alpha 1) over amacrine and horizontal cells; and the less preferred GDNF receptor (GFR alpha 2) over ganglion cells, amacrine cells and photoreceptors.[1]

References

  1. Overlapping and specific patterns of GDNF, c-ret and GFR alpha mRNA expression in the developing chicken retina. Karlsson, M., Lindqvist, N., Mayordomo, R., Hallböök, F. Mech. Dev. (2002) [Pubmed]
 
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