- Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site. Ulaner, G.A., Vu, T.H., Li, T., Hu, J.F., Yao, X.M., Yang, Y., Gorlick, R., Meyers, P., Healey, J., Ladanyi, M., Hoffman, A.R. Hum. Mol. Genet. (2003)