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MeSH Review

Osteosarcoma

 
 
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Disease relevance of Osteosarcoma

 

Psychiatry related information on Osteosarcoma

 

High impact information on Osteosarcoma

  • Expression of wild-type, but not mutant, DOCK4 in mouse osteosarcoma cells with a deletion of the endogenous gene suppresses growth in soft agar and tumor invasion in vivo [8].
  • The presence of increased levels of P-glycoprotein in the osteosarcoma was significantly associated with a decreased probability of remaining event-free after diagnosis (P = 0.002) [9].
  • Using DNA transfection, we show that TGF-beta stimulates the activity of the mouse alpha 2(l) collagen promoter 5- to 10-fold in mouse NIH 3T3 and rat osteosarcoma cells [10].
  • However, HTLV-I-infected human osteosarcoma cells do not express IL2R alpha-CAT constructs [11].
  • A 140 kd protein was bound by the affinity matrix from octylglucoside extracts of MG-63 human osteosarcoma cells and specifically eluted with the synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro [12].
 

Chemical compound and disease context of Osteosarcoma

 

Biological context of Osteosarcoma

 

Anatomical context of Osteosarcoma

 

Gene context of Osteosarcoma

 

Analytical, diagnostic and therapeutic context of Osteosarcoma

References

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  20. Oncostatin M induces bone loss and sensitizes rat osteosarcoma to the antitumor effect of Midostaurin in vivo. Brounais, B., Chipoy, C., Mori, K., Charrier, C., Battaglia, S., Pilet, P., Richards, C.D., Heymann, D., Rédini, F., Blanchard, F. Clin. Cancer Res. (2008) [Pubmed]
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