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Lockwood, A.H.

Shy-Drager syndrome with abnormal respirations and antidiuretic hormone release.

A patient with Shy-Drager syndrome exhibited a partial defect in antidiuretic hormone (ADH) release, and cluster breathing, an indication of pontomedullary respiratory center damage, with a normal CO2 response curve. This extends the spectrum of abnormalities associated with the degenerative disease of the central nervous system. The presence of a pontomedullary respiratory pattern without an impaired CO2 response curve suggests that neurons that determine respiratory rhythm function independently from those that function as chemoreceptors.[1]

References

Shy-Drager syndrome with abnormal respirations and antidiuretic hormone release. Lockwood, A.H. Arch. Neurol. (1976) [Pubmed]

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