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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Satisfaction with onychomycosis treatment. Pulse versus continuous dosing.

The purpose of this study, which involved two dermatology clinics and two podiatric medical clinics, was to determine whether a difference exists in patient-reported satisfaction and compliance between continuous terbinafine therapy and pulse-dose itraconazole therapy for the treatment of toenail onychomycosis. Patients in this multicenter, open-label, cross-sectional study had previously completed treatment with either oral terbinafine or oral itraconazole for toenail onychomycosis. Patients were interviewed by telephone to assess clinical outcomes, compliance, and satisfaction with treatment; clinical data were collected by medical chart review. Patients reported significantly greater ease and convenience of treatment and higher overall satisfaction with continuous terbinafine therapy compared with pulse-dose itraconazole therapy.[1]

References

  1. Satisfaction with onychomycosis treatment. Pulse versus continuous dosing. Warshaw, E.M., Bowman, T., Bodman, M.A., Kim, J.J., Silva, S., Mathias, S.D. Journal of the American Podiatric Medical Association. (2003) [Pubmed]
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