The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound

Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

[search][options]

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Shibuya, Y. et al.

Shibuya, Tanimoto, Umeda, Yokoo, Komori,

Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil for tongue cancer.

Induction chemotherapy consisting of one cycle of docetaxel, cisplatin and 5-fluorouracil (5-FU) was evaluated for its primary effects on squamous cell carcinoma of the tongue. The patients were five men and one woman, 50 to 67 (mean 57.8) years of age. Clinical staging of the tongue cancers showed two patients with stage III and four with stage IV disease. All patients underwent one cycle of intravenous chemotherapy with docetaxel (60 mg/m2, on day 1), cisplatin (10 mg/m2, from days 1 to 5) and 5-FU (500 mg/body, from days 1 to 5) before surgical operation. The overall response rate was 83.3% (five PRs and one NC), with two cases with grade II A in the Ohboshi & Shimosato classification and four with grade II B. The main side effect was severe neutropenia, which was effectively managed with granulocyte colony-stimulating factor (G-CSF). In conclusion, induction chemotherapy with docetaxel, cisplatin and 5-FU for tongue cancer was tolerated well by all the patients and showed an excellent response rate in spite of only one cycle of administration.[1]

References

Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil for tongue cancer. Shibuya, Y., Tanimoto, H., Umeda, M., Yokoo, S., Komori, T. The Kobe journal of medical sciences. (2004) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg