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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Severe hyperhomocysteinaemia and 5-oxoprolinuria secondary to antiproliferative and antimicrobial drug treatment.

A hitherto healthy 7-year-old girl underwent antiproliferative and antibiotic treatment owing to the diagnosis of T-cell lymphoma and concomitant bacterial infection. She developed an encephalopathic crisis associated with metabolic acidosis, hyponatraemia and severe hyperhomocysteinaemia and 5-oxoprolinuria. Laboratory tests normalized completely after recovery. Primary defects in glutathione metabolism could be excluded.[1]

References

  1. Severe hyperhomocysteinaemia and 5-oxoprolinuria secondary to antiproliferative and antimicrobial drug treatment. Schwahn, B., Kameda, G., Wessalowski, R., Mayatepek, E. J. Inherit. Metab. Dis. (2005) [Pubmed]
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