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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Peracetic acid in the disinfection of a hospital water system contaminated with Legionella species.

OBJECTIVE: To assess the efficacy of an alternative disinfection method for hospital water distribution systems contaminated with Legionella. METHODS: Disinfection with peracetic acid was performed in a small hospital contaminated with L. pneumophila serotype 1. The disinfectant was used at concentrations of 50 ppm (first three surveillance phases) and 1,000 ppm (fourth surveillance phase) for 30 minutes. RESULTS: Environmental monitoring revealed that disinfection was maintained 1 week after treatment; however, levels of recontamination surpassing baseline values were detected after approximately 1 month. Comparison of water temperatures measured at the distal outlets showed a statistically significant association between temperature and bacterial load. The circulating water temperature was found to be lower in the two wards farthest away from the hot water production plant than in other wards. It was thought that the lower water temperature in the two wards promoted the bacterial growth even after disinfection. CONCLUSION: Peracetic acid may be useful in emergency situations, but does not provide definitive protection even if used monthly.[1]


  1. Peracetic acid in the disinfection of a hospital water system contaminated with Legionella species. Ditommaso, S., Biasin, C., Giacomuzzi, M., Zotti, C.M., Cavanna, A., Ruggenini Moiraghi, A. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. (2005) [Pubmed]
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