Disease relevance of Environmental Monitoring

• Therefore, this study suggests that the GSTT1 genetic polymorphism has the potential to affect the biological monitoring of PAHs with urinary 1-OHP, and might act as a genetic factor in PAH-related toxicity [1].
• Usefulness of L-[methyl-11C] methionine-positron emission tomography as a biological monitoring tool in the treatment of glioma [2].
• The results presented in this investigation indicate that biological monitoring of the pyrene metabolite 1-hydroxypyrene is a useful indicator of a general PAH exposure, but cannot replace personal air sampling for assessing the lung cancer risk of individuals [3].

High impact information on Environmental Monitoring

• PURPOSE: An environmental and biological monitoring survey was conducted to evaluate current exposures to aniline and o-toluidine in the rubber chemicals department [4].
• IL-6 and TNF-alpha plasma concentrations may be useful in monitoring biological activity of bryostatin 1 [5].
• Broadening of these studies to encompass environmental monitoring, aimed at the identification of environmental cofactors which may synergize with early allergen exposure, is therefore a logical step for the future research [6].
• Biological monitoring of cadmium workers [7].
• The utility and power of 3H NMR spectroscopy as a technique for monitoring biological systems in vivo is illustrated with glucose metabolism in erythrocytes [8].

Chemical compound and disease context of Environmental Monitoring

• Monitoring acrylic fiber workers for liver toxicity and exposure to dimethylacetamide. 1. Assessing exposure to dimethylacetamide by air and biological monitoring [9].
• Toxicity of and biological monitoring for 1,3-diamino-2, 4, 6-trinitrobenzene and other nitro-amino derivatives of benzene and chlorobenzene [10].

Biological context of Environmental Monitoring

• For the bivalve mollusc Crassostrea virginica, a species frequently used in studies on the toxicology and environmental monitoring of metals, the primary structure for MT has been deduced from analysis of the proteins and cDNA [11].
• The results of this work, supported by experimental validation, can aid in understanding the metabolism and toxic effects of uranium with potential applications to biological monitoring as well as chelation treatment of uranium body burden [12].
• Transmembrane receptors in microorganisms, such as sensory histidine kinases and methyl-accepting chemotaxis proteins, are molecular devices for monitoring environmental changes [13].
• Biological and environmental monitoring of occupational exposure to cyclophosphamide in industry and hospitals [14].
• Biological monitoring of carbon disulphide: kinetics of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA) in exposed workers [15].

Anatomical context of Environmental Monitoring

• Low-level exposure to methylmercury modifies muscarinic cholinergic receptor binding characteristics in rat brain and lymphocytes: physiologic implications and new opportunities in biologic monitoring [16].
• To evaluate the usefulness of the placenta for monitoring environmental lead and cadmium exposure, concentrations of both metals were measured in placentas (n = 86) with atomic absorption spectrometry [17].

Associations of Environmental Monitoring with chemical compounds

• Biological monitoring screening of patients provided antineoplastic drugs including adriamycin, cyclophosphamide, 5-fluorouracil, methotrexate, and vincristine [18].
• This report describes an extensive program of scientific epidemiologic monitoring of the safety of acyclovir during the first five years following approval [19].
• Interest of genotyping and phenotyping of drug-metabolizing enzymes for the interpretation of biological monitoring of exposure to styrene [20].
• We conclude that our data indicate a possible mechanism of FA carcinogenicity in humans and that DPC can be used as a method for biological monitoring of exposure to FA [21].
• Determination of S-phenylmercapturic acid in the urine--an improvement in the biological monitoring of benzene exposure [22].

Gene context of Environmental Monitoring

• Since large variations in CYP2E1 activity exist in the human population (at least 5-fold range), it seems justified to take into account the activity of this enzyme in an individual for an accurate interpretation of biological monitoring of exposure to NMP when relying on 5HNMP and/or 2HMSI determination in urine [23].
• The results are discussed with reference to the possible use of plaice P450 1A1 cDNA as a probe for environmental monitoring studies [24].
• This shows that the delta Hcal is a sensitive parameter for monitoring environmental changes of rhodopsin and opsin [25].
• Furthermore, CYP utilized to construct biosensors for the determination of substrates important in environmental monitoring, pharmaceutical industry and clinical practice [26].
• The biological monitoring included the measurement of delta-aminolevulinic acid dehydratase activity (ALAD) and the concentration of zinc-protoporphyrin (ZPP), blood lead (Pb-B) and hemoglobin (Hb) [27].

Analytical, diagnostic and therapeutic context of Environmental Monitoring

• Chromatographic determination of amines in biological fluids with special reference to the biological monitoring of isocyanates and amines. IV. Determination of 1,6-hexamethylenediamine in human urine using capillary gas chromatography and selective ion monitoring [28].
• Good recoveries and correlation with spike levels were observed, suggesting this immunoassay is valuable for environmental monitoring and toxicological studies at parts per trillion levels of permethrin [29].
• The influence of skin moisture on the dermal absorption of propoxur in human volunteers: a consideration for biological monitoring practices [30].
• The increase in DNA strand-breaks measured by comet assay suggests this test is valid for the biological monitoring of workers exposed to genotoxic compounds such as chromium (VI) [31].
• Direct synthesis of aflatoxin B1-N7 guanine adduct: a reference standard for biological monitoring of dietary aflatoxin exposure in molecular epidemiological studies [32].

References