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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The effect of probiotics on the genotoxicity of furazolidone.

Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T20 (81.9%).[1]


  1. The effect of probiotics on the genotoxicity of furazolidone. Raipulis, J., Toma, M.M., Semjonovs, P. Int. J. Food Microbiol. (2005) [Pubmed]
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