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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Critically short telomeres are associated with sperm DNA fragmentation.

The influence of critical telomeric attrition, a well-known trigger of apoptosis and cell arrest, on sperm DNA fragmentation was studied in late-generation knockout mice for Terc, the RNA component of telomerase, as a model of choice. Terc knockout mice had a sixfold mean increase in the percentage of sperm cells with fragmented DNA.[1]

References

  1. Critically short telomeres are associated with sperm DNA fragmentation. Rodríguez, S., Goyanes, V., Segrelles, E., Blasco, M., Gosálvez, J., Fernández, J.L. Fertil. Steril. (2005) [Pubmed]
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