Genetic susceptibility to type 1 diabetes.
The recent discovery of PTPN22 as a novel susceptibility gene in human type 1 diabetes and continued progress in defining genes in animal models of the disease mark a fruitful period in the field of type 1 diabetes genetics. In addition, the similarities of the genetic and functional aspects across species have been substantiated. Future genome-wide association studies will reveal more loci, each providing a piece to the genetic puzzle of autoimmune disease.[1]References
- Genetic susceptibility to type 1 diabetes. Maier, L.M., Wicker, L.S. Curr. Opin. Immunol. (2005) [Pubmed]
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