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MeSH Review

Autoimmune Diseases

 
 
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Disease relevance of Autoimmune Diseases

 

Psychiatry related information on Autoimmune Diseases

 

High impact information on Autoimmune Diseases

  • The pathogenic roles of B cells in autoimmune diseases occur through several mechanistic pathways that include autoantibodies, immune complexes, dendritic and T cell activation, cytokine synthesis, chemokine-mediated functions, and ectopic neolymphogenesis [11].
  • Disruption of the LT/TNF/LIGHT network alleviates inflammation in certain autoimmune disease models, but decreases resistance to selected pathogens [12].
  • IL-2 is necessary to destroy self-reactive lymphocytes and thus favors peripheral tolerance to self-antigens, whereas IL-15 favors the persistence of lymphocytes involved in the memory and effector responses to invading pathogens but risks the development of inflammatory autoimmune diseases [13].
  • Identifying Idd genes and defining their biologic functions should further our understanding of autoimmune disease pathogenesis and facilitate development of new treatments for diabetes [14].
  • Thus it may not be necessary to identify the target autoantigen to suppress an organ-specific autoimmune disease via oral tolerance; it is necessary only to administer orally a protein capable of inducing regulatory cells that secrete suppressive cytokines [15].
 

Chemical compound and disease context of Autoimmune Diseases

 

Biological context of Autoimmune Diseases

 

Anatomical context of Autoimmune Diseases

 

Gene context of Autoimmune Diseases

 

Analytical, diagnostic and therapeutic context of Autoimmune Diseases

References

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