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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution.

Musashi-1 is involved in maintenance of neural stem cells. In the rat stomach, we found some cells in the luminal compartment of the mucosa that stained positively for Musashi-1. These cells were distinct from other cells of epithelial lineage, except for parietal cells, and coexpressed HES5. The Musashi-1-positive cells exfoliated after damage, while Musashi-1 expression in neck cells were upregulated, and proliferating cells diminished before reappearing and increasing in number thereafter. We conclude that a subpopulation of parietal cells acts as a source of Musashi-1, which contributes to rapid re-epithelization by restoration of stem cells and regulation of cell differentiation.[1]

References

  1. Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution. Nagata, H., Akiba, Y., Suzuki, H., Okano, H., Hibi, T. FEBS Lett. (2006) [Pubmed]
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