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 Qian,  Xu,  
 

Effect of polysaccharide extracted from Glaciecola polaris on the protection of mouse macrophages from oxidative injury.

The effect of the protein-bound polysaccharide extracted from Glaciecola polaris (PSG) was investigated in vitro in the protection of oxidatively-injured mouse macrophages stressed by tert-butyl hydroperoxide (tbOOH) or by oxidatively modified low-density lipoprotein (Ox-LDL). The results showed that PSG treatments to protect the macrophages from oxidative injury was effective and the macrophage colony-stimulating factor (M-CSF) exhibited some similar effects. It was speculated that both M-CSF and PSG could protect macrophages from oxidative injury. The results suggested that the effects of PSG were associated with its capability of inducing M-CSF expression.[1]

References

  1. Effect of polysaccharide extracted from Glaciecola polaris on the protection of mouse macrophages from oxidative injury. Qian, G., Xu, Z. Bioresour. Technol. (2007) [Pubmed]
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