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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Influence of infusion flow rates on central venous pressure measurements through multi-lumen central venous catheters in intensive care.

OBJECTIVE: To study the influence on central venous pressure (CVP), measured at the distal port, of crystalloid infusions administered through the proximal port(s) of a central venous multi-lumen catheter. PATIENTS: Thirty-one intensive care patients. INTERVENTIONS: CVP was measured at the distal port of a multi-lumen catheter inserted in the subclavian or internal jugular vein. Using the proximal port(s), saline (0.9%) was infused at rates varying from 2[Symbol: see text]ml/h to 14,340[Symbol: see text]ml/h. RESULTS: CVP measured before the infusion and during infusion (after 30[Symbol: see text]s to 1[Symbol: see text]min) were not significantly different. Positive pressure ventilation with PEEP (5.6[Symbol: see text]+/-[Symbol: see text]2.5 cmH(2)O) and/or norepinephrine infusion (0.25[Symbol: see text]+/-[Symbol: see text]0.21[Symbol: see text]mug[Symbol: see text]kg(-1)[Symbol: see text]min(-1)) did not produce any significant change in CVP during infusion. CONCLUSION: The administration of crystalloids at different flow rates through the proximal port(s) of a multi-lumen catheter placed in the superior vena cava does not affect CVP measurement at the distal port, even in mechanically ventilated patients or patients receiving vasopressors.[1]

References

  1. Influence of infusion flow rates on central venous pressure measurements through multi-lumen central venous catheters in intensive care. Lakhal, K., Ferrandière, M., Lagarrigue, F., Mercier, C., Fusciardi, J., Laffon, M. Intensive care medicine. (2006) [Pubmed]
 
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