The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Glucose metabolism in batch and continuous cultures of Gluconacetobacter diazotrophicus PAL 3.

Periplasmic glucose oxidation (by way of a pyrrolo-quinoline-quinone [PQQ]-linked glucose dehydrogenase [ GDH]) was observed in continuous cultures of Gluconacetobacter diazotrophicus regardless of the carbon source (glucose or gluconate) and the nitrogen source (N(2) or NH(3)). Its synthesis was stimulated by conditions of high energetic demand (i.e., N(2)-fixation) and/or C-limitation. Under C-excess conditions, PQQ- GDH synthesis increased with the glucose concentration in the culture medium. In batch cultures, PQQ- GDH was actively expressed in very early stages with higher activities under conditions of N(2)-fixation. Hexokinase activity was almost absent under any culture condition. Cytoplasmic nicotinamide adenine dinucleotide (NAD)-linked glucose dehydrogenase ( GDH) was expressed in continuous cultures under all tested conditions, and its synthesis increased with the glucose concentration. In contrast, low activities of this enzyme were detected in batch cultures. Periplasmic oxidation, by way of PQQ- GDH, seems to be the principal pathway for metabolism of glucose in G. Diazotrophicus, and NAD- GDH is an alternative route under certain environmental conditions.[1]

References

  1. Glucose metabolism in batch and continuous cultures of Gluconacetobacter diazotrophicus PAL 3. Luna, M.F., Bernardelli, C.E., Galar, M.L., Boiardi, J.L. Curr. Microbiol. (2006) [Pubmed]
 
WikiGenes - Universities