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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Transformation of horse skin cells by type-C sarcoma viruses.

A horse skin cell line (E. Derm, NBL-6, CCL-57) was susceptible to focus formation by the Kirsten mouse sarcoma virus, feline sarcoma virus (ST stain) and the MSV pseudotypes with woolly monkey, gibbon monkey, RD-114, AT-124, baboon placenta and murine xenotropic (BALB/c 3T3 and C57L/JD) type-C viruses. Foci were detected within 5 days after infection and the transformed cells continued to produce infectious virus and group-specific antigen of their respective type-C leukemia viruses. The transformation efficiency of various type-C sarcoma viruses in horse cells was also very high.[1]


  1. Transformation of horse skin cells by type-C sarcoma viruses. Rhim, J.S., Ro, H.S., Kim, E.B., Gilden, R.V., Huebner, R.J. Int. J. Cancer (1975) [Pubmed]
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