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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

In vitro activity of 11 antibiotics against 74 anaerobes isolated from pediatric intra-abdominal infections.

The in vitro activity of 11 antimicrobials was tested against 74 recent anaerobic isolates obtained from pretreatment cultures in pediatric patients with complicated intra-abdominal infections using the CLSI M11-A-6 agar dilution method. Carbapenems, beta-lactamase inhibitor combinations and metronidazole retained good activity, while all Bacteroides fragilis group species produced beta-lactamase and were penicillin resistant and 43% were either intermediately susceptible or resistant to clindamycin. Cefoxitin had moderate activity against B. fragilis but poor activity against Bacteroides thetaiotaomicron and other B. fragilis group isolates.[1]

References

  1. In vitro activity of 11 antibiotics against 74 anaerobes isolated from pediatric intra-abdominal infections. Goldstein, E.J., Citron, D.M., Vaidya, S.A., Warren, Y.A., Tyrrell, K.L., Vreni Merriam, C., Fernandez, H. Anaerobe (2006) [Pubmed]
 
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